SkyPRP — a third-generation platelet-rich plasma extraction platform. Closed system, needle-free, Class 2b certified, developed and manufactured by SKY Biotechnology.
The healing effects of platelet-rich plasma are due to the growth factors released by platelets, which stimulate the healing response. SkyPRP is built to release those growth factors as quickly and safely as possible: blood is drawn into an anticoagulant syringe, separated by centrifugation at 3,500 rpm (approximately 1,600 G) for 5 minutes, and the Buffy Coat is extracted in full through a specially designed narrow-neck connector — all within a closed system.
Two kits on one closed-system platform.
The narrow-neck design allows full extraction of the Buffy Coat, enabling the practitioner to obtain visibly rich plasma within approximately 10 minutes. The needle-free design ensures PRP–PPP isolation in a closed system, eliminating the risk of contamination.
Developed for therapeutic applications where a higher concentration of growth factors is required, and preferred in cases where a single syringe is insufficient.
The extraction platform behind both kits: closed-system safety, efficient blood separation and precise PRP extraction through the narrow-neck connector.
| Step | Parameter |
|---|---|
| Blood collection | Drawn into an anticoagulant syringe |
| Centrifugation | 3,500 rpm ≈ 1,600 G · 5 minutes |
| Ready to use | PRP ready in approximately 10 minutes |
| Extraction | Narrow-neck connector · full Buffy Coat |
| System | Closed, needle-free · PRP–PPP isolation |
| Certification | Class 2b medical device |
| Compatibility | Compatible with all centrifuges |
Refer to the Instructions for Use for the full intended purpose, contraindications and warnings.
Per the Instructions for Use. Intended for use by qualified healthcare professionals.
SkyPRP is a third-generation, sterile single-use kit for preparing autologous platelet-rich plasma from the patient own peripheral blood inside a closed circuit. There is no drug and no added active substance: the working principle is mechanical concentration, blood is drawn into an anticoagulant syringe, separated by centrifugation at 3,500 rpm, approximately 1,600 G, for five minutes, and the Buffy Coat is then extracted in full through a specially designed narrow-neck connector, so the growth factors held in the platelets, among them PDGF, TGF-beta and VEGF, are delivered at concentration to the treatment site. The clinical problem it addresses is reproducibility and contamination risk in chairside PRP preparation: the needle-free closed design isolates PRP from platelet-poor plasma without opening the circuit, and usable plasma is ready in roughly ten minutes. SkyPRP is certified as a Class 2b medical device, works with existing centrifuge equipment without dedicated hardware, and is manufactured in-house by SKY Biotechnology under an ISO 13485 certified quality management system.
Parameter-level view of the SkyPRP closed system. Refer to the Instructions for Use for the full intended purpose, contraindications and warnings.
| Component | Specification | Clinical advantage | Certification |
|---|---|---|---|
| Blood collection, anticoagulant syringe | Whole blood drawn directly into the anticoagulant syringe of the kit | Prevents coagulation during handling and separation, protecting platelet integrity before concentration | Class 2b medical device · ISO 13485 certified QMS |
| Centrifugation cycle | 3,500 rpm, approximately 1,600 G, for 5 minutes | A single defined cycle achieves maximum separation, which is what makes the platelet yield reproducible between operators | Class 2b medical device · ISO 13485 certified QMS |
| Narrow-neck extraction connector | Full extraction of the Buffy Coat layer | Recovers the platelet-rich fraction in full while limiting red cell carry-over, giving visibly rich plasma | Class 2b medical device · ISO 13485 certified QMS |
| Closed, needle-free circuit | PRP and PPP isolated without opening the system | Contamination risk is minimised because the circuit is never broken during separation and extraction | Class 2b medical device · ISO 13485 certified QMS |
| Time to usable PRP | Approximately 10 minutes from draw to application | Fits a single chairside visit, so the patient is treated in the same appointment | Class 2b medical device · ISO 13485 certified QMS |
| SkyPRP Uni, single syringe | One-syringe configuration on the SkyPRP Injector platform | The standard configuration for routine indications, with full Buffy Coat extraction | Class 2b medical device · ISO 13485 certified QMS |
| SkyPRP Duo, dual syringe | Two-syringe configuration on the same platform | Developed for therapeutic applications requiring a higher concentration of growth factors, or where a single syringe is insufficient | Class 2b medical device · ISO 13485 certified QMS |
| Centrifuge compatibility | Compatible with all centrifuges | No dedicated hardware investment, so a clinic can adopt the kit against equipment it already owns | Class 2b medical device · ISO 13485 certified QMS |
Common questions from distributors and clinicians about SkyPRP.
The distinguishing features are the closed, needle-free circuit and the narrow-neck extraction connector. Earlier generations require the operator to open the tube and pipette the plasma layer by hand, which introduces both contamination risk and operator-to-operator variability. In SkyPRP the separation and the extraction happen without breaking the circuit, and the Buffy Coat is drawn off in full through the connector rather than judged by eye.
A single cycle at 3,500 rpm, approximately 1,600 G, for five minutes. Usable platelet-rich plasma is ready roughly ten minutes after the draw. The kit is compatible with all centrifuges, so no dedicated equipment purchase is needed.
Both run on the same SkyPRP Injector closed-system platform. Uni is the single-syringe configuration for routine use. Duo is the dual-syringe configuration, developed for therapeutic applications where a higher concentration of growth factors is required or where one syringe is not sufficient for the treatment area.
SkyPRP is certified as a Class 2b medical device and is manufactured under an ISO 13485 certified quality management system. Availability, specifications and regulatory status may vary by country; the Instructions for Use govern the intended purpose, contraindications and warnings.
Per the Instructions for Use and for use by qualified healthcare professionals, the indicated areas are orthopaedic applications, sports medicine, dermatology and aesthetics, hair restoration and wound healing support.
SkyPRP is developed and produced in-house by SKY Biotechnology at its own facility in Pendik, Istanbul, Turkiye, under an ISO 13485 certified quality management system. The company exports to more than fifty countries.
Technical specifications, regulatory documentation and catalogs are available to qualified partners on request.
Product information is provided for healthcare professionals, distributors and business partners and does not constitute medical advice. Availability, specifications and regulatory status may vary by country.