ORTHOPAEDICS · FLAGSHIP PRODUCT

Intraarticular Implant Gels

Sterile, single-use intra-articular hyaluronic acid gels for viscosupplementation in osteoarthritis and joint disorders. Four grades, developed and manufactured by SKY Biotechnology.

Overview

Intraarticular implant gels are injectable viscoelastic devices used to supplement the synovial fluid of joints affected by osteoarthritis and degenerative disorders. By supporting lubrication and shock absorption, they are intended to improve joint mobility and comfort. SkyVisc covers four grades on a common concentration range of 10–30 mg/mL: SkyVisc Pure (sodium hyaluronate alone), SkyVisc + (with L-proline), SkyVisc GGP (with L-proline, glycine and N-acetyl glucosamine) and SkyVisc Cross (the cross-linked grade) — three linear gels and one cross-linked, from a single source. As the flagship line of SKY Biotechnology, these products are developed and produced in-house.

Product Line

Four grades of intra-articular hyaluronic acid gel — three linear, one cross-linked.

SkyVisc PureHA only

Highly purified sodium hyaluronate with no additives. Linear gel. Pre-filled syringe from 1 to 5 mL, in concentrations from 10 to 30 mg/mL.

SkyVisc +HA + Proline

Hyaluronic acid with L-proline, an amino acid that is a structural component of collagen. Linear gel. Pre-filled syringe (1–5 mL) or flacon (5 or 10 mL), in concentrations from 10 to 30 mg/mL.

SkyVisc GGPHA + Proline + Glycine + NAGA

Hyaluronic acid with L-proline, glycine and N-acetyl glucosamine — the constituents behind the GGP name (Glucosamine, Glycine, Proline). Linear gel. Pre-filled syringe (1–5 mL) or flacon (5 or 10 mL), in concentrations from 10 to 30 mg/mL.

SkyVisc CrossCross-linked HA

Highly purified cross-linked hyaluronic acid of bacterial origin. Cross-linking bonds the polymer chains into a network that maintains its shape longer and slows disintegration. One injection per treatment. Pre-filled syringe (1–5 mL), 10 to 30 mg/mL.

SkyVisc Pure SkyVisc + SkyVisc GGP SkyVisc Cross
Hyaluronic acid 10 – 30 mg/mL 10 – 30 mg/mL 10 – 30 mg/mL 10 – 30 mg/mL
Concentrations 10 / 14 / 15 / 20 / 24 / 25 / 30 mg/mL 10 / 14 / 15 / 20 / 24 / 25 / 30 mg/mL 10 / 14 / 15 / 20 / 24 / 25 / 30 mg/mL 10 / 14 / 15 / 20 / 24 / 25 / 30 mg/mL
Additional components L-proline L-proline, glycine, N-acetyl glucosamine
Bonding Linear Linear Linear Cross-linked
Syringe 1 / 2 / 2.5 / 3 / 4 / 5 mL 1 / 2 / 2.5 / 3 / 4 / 5 mL 1 / 2 / 2.5 / 3 / 4 / 5 mL 1 / 2 / 2.5 / 3 / 4 / 5 mL
Flacon 5 / 10 mL 5 / 10 mL
Formulation Sodium hyaluronate in buffer (sodium dihydrogen phosphate, disodium hydrogen phosphate, sodium chloride) — with L-proline in SkyVisc +; with L-proline, glycine and N-acetyl glucosamine in SkyVisc GGP.

All SkyVisc grades: sterile viscoelastic solution, single use. Shelf life: 2 years. Storage: 2–25 °C — no cold chain required. CE marked.

Technical Highlights

Linear and cross-linked in one rangeThree linear grades and one cross-linked grade, so a single supplier covers both formulation types. Grade selection and injection regimen follow the Instructions for Use and clinical judgement.
No cold chain requiredAll SkyVisc grades are stored between 2 °C and 25 °C with a shelf life of 2 years — no refrigerated transport or storage, which simplifies distribution in warm-climate markets.
Syringe and flacon presentationsEvery grade is offered as a pre-filled syringe from 1 to 5 mL, in seven concentrations from 10 to 30 mg/mL. SkyVisc + and GGP are additionally available as 5 and 10 mL flacons.
In-house manufacturingDeveloped and produced by SKY Biotechnology at our own facility under an ISO 13485 certified quality management system.
CE markedSkyVisc is CE marked. Refer to the Instructions for Use for the full intended purpose, contraindications and warnings.

Indications & Use Areas

Per the Instructions for Use. Intended for use by qualified healthcare professionals.

Osteoarthritis of the kneeHip and shoulder joint disordersDegenerative joint diseaseDegenerative meniscopathyCartilage problems associated with synovial fluid deficiency

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Product information is provided for healthcare professionals, distributors and business partners and does not constitute medical advice. Availability, specifications and regulatory status may vary by country.

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